Chlorantraniliprole is an o-formamidobenzamide insecticide with the test code DPX-E2Y45.
Chemical name：3-Bromo-4-chloro-1-(3-chloro-2-pyridyl)-2-methyl-6-(methylcarbamoyl)pyrazole-5-carboxanilide
CAS No.:500008-45-7
Structure:
Action:an acting agent of carnitine receptor
Target:Broad-spectrum, high-efficiency control of chewing mouthpart pests on fruit trees, vegetables, field crops, specialty crops and lawns. In addition to preventing and controlling lepidopteran pests, chlorantraniliprole can also control Colorado beetles, leafhoppers, etc. with increased dosage. At the same time, it has an inhibitory effect on whiteflies, and is widely used in rice, soybeans, cotton, fruits and vegetables. other crops
Since its launch in 2008, chlorantraniliprole has been sold in more than 100 countries in the world, covering almost all major markets. Its excellent insecticidal effect has made it a star product of DuPont and the world’s largest insecticide. The product was acquired by FMC in 2017, and its related intellectual property, including patents, registrations and data packages, was transferred to FMC.
Under the current situation of stricter and stricter requirements for the safety of pesticides, high-efficiency, low-toxicity, and environmentally friendly pesticides will be more favored. On the basis of existing compounds, structural transformations are carried out to find new safer and more environmentally friendly pesticides. It will be a research hotspot in the future, and it will also be the future road for the development of pesticides in the direction of green pesticides.
DuPont, as the original research company of chlorantraniliprole, has filed a large number of patent applications for this product. In this paper, the CAS accession number, chemical name and structural formula of the compound are searched in the Caplus database in the STN search platform, and the applicant information is tracked and retrieved. , to study and analyze DuPont’s patent application status, patent layout and R&D strategy for this product, in order to provide a certain reference for relevant R&D enterprises in the domestic pesticide field.
1.Compound Patent
When entering China, the general formula compound, specific compound, composition and control method were authorized. This patent is a very important compound patent for DuPont and FMC and will expire on August 13, 2022.
2.Composition patent
In the field of pesticides, composition patents are usually regarded as peripheral patents, but in terms of subsequent market development and application, infringement compensation after patent authorization, etc., in addition to core compound patents, some composition patents in the form of open drafting are also very important.
3.Preparation patent
4.Application method and use patent
In addition to submitting the PCT application WO2003015518A1 on the filing date of the original compound patent, DuPont also applied for a series of patents on the application method and use of chlorantraniliprole (Table 4), and further studied how to improve crop yield and enhance killing insect activity and range, and develop many more uses.
5.Summary
Through the statistics of DuPont’s chlorantraniliprole related patent technologies, the research and development process and patent layout of DuPont’s chlorantraniliprole are analyzed. DuPont has carried out comprehensive and in-depth research and development of chlorantraniliprole. On the same day as the core compound patent application, it submitted the patent for the preparation method and the application method, and then further on the compound structure improvement, composition, preparation method and Relevant patent applications have been submitted for intermediates, application methods and new uses. A series of multi-faceted patent applications have formed a perfect patent chain, providing a strong force for DuPont to obtain market share and maximize commercial benefits of pesticides. At the same time, it also prolongs the life cycle of the product as much as possible.
In the field of pesticides, most domestic applications focus on structural improvement of some pesticides already on the market, that is, keeping the parent structure of the compound unchanged, and modifying some of its structural fragments in order to improve the insecticidal activity and increase the insecticidal broad spectrum. Chinese pesticide research and development enterprises can learn from DuPont’s patent layout and strategy on chlorantraniliprole, carry out a comprehensive patent layout for research and development products, and formulate appropriate business strategies based on their own research and development level and the actual situation of domestic and foreign markets. It is believed that with the gradual enhancement of my country’s innovation capability, more new pesticide varieties with independent intellectual property rights will be developed, and continuous research and development will support the Chinese agrochemical industry to compete in the world. Later, related patent applications were further submitted for compound structure improvement, compositions, preparation methods and intermediates, application methods and new uses, etc. A series of multi-faceted patent applications formed a perfect patent chain and obtained pesticides for DuPont. It provides a strong guarantee for the maximization of market share and commercial interests, and at the same time, it also prolongs the life cycle of the product as much as possible.
Post time: Aug-22-2022